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Secretin is encoded by the SCT gene

Post-transplant diabetes mellitus and preexisting liver disease a bidirectional relationship affecting treatment and management

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Upon ligand binding, TR II phosphorylates and activates TR I, forming a heteromeric receptor complex that initiates downstream signaling through both SMAD-dependent and SMAD-independent pathways, such as ERK, p38, JNK, and PI3K-Akt cascades [33, 36, 39]

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