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Formulation strategies are also assessed with consideration for vehicle composition and tolerability, helping ensure that selected systems are appropriate for both oral and IV administration in PK and GLP study settings
Available from: Desprs JP, Carpentier AC, Tchernof A, Neeland IJ, Poirier P
By restoring protein folding homeostasis and secretory enzyme trafficking, FGF21 enhances digestive enzyme secretion without increasing protein synthesis (259)
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Other GLP-1 receptor agonists and various weight loss interventionswhether pharmacological, dietary, or surgicalare also associated with increased gallbladder-related risks, though the magnitude may vary by approach and agent
