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Most EECs are considered open-type cells, resembling a bottleneck shape, with an apical membrane in direct contact with the intestinal lumen, as well as a basolateral membrane in close proximity to blood vessels and neurons that innervate the intestinal mucosa and come in close contact with the epithelial layer 82

It acts as an electrolyte replenisher rather than being a mixed ingredient in most other routine prescription drugs

Clinical Evidence on Wegovy and Sertraline Safety Together Published safety data shows no contraindication between GLP-1 agonists and selective serotonin reuptake inhibitors (SSRIs) like sertraline