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The deficiency of NRF2 promotes osteoclast differentiation and osteoclast activity, leading to an increase in bone resorption

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The capsule is chemically engineered to remain intact through the stomach's acidic environment and dissolve only in the small intestine the optimal site for bicarbonate absorption

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Wood SJ, Berger GE, Wellard RM, Proffitt TM, McConchie M, Berk M, et al