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People with diabetes are already at risk of hypoglycemia simply because of the nature of the condition

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Because preservative effectiveness is only required to be demonstrated for 28 days after first entry, standard multiple-dose vial practice, reflected in CDC injection safety guidance, is to date the vial at first puncture and discard it 28 days later

Always ensure you consult practitioners who understand EDS well, and approach treatment decisions informed by both evidence and your personal values

After first puncture, the 28-day multi-dose window starts, and refrigeration at 2-8C is consistently cited as the documented best practice in community and pharmaceutical references