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While this mechanism remains speculative, the underlying physiology of cryotherapy-induced blood flow changes supports the concept
10.1016/j.celrep.2018.02.051 Cell Rep
Dihexa, with its combined N-hexanoic-Tyr-Ile-(6) aminohexanoic amide structure, exhibited a significantly extended half-life of 335.5 9.5 min, confirming that both N- and C-terminal modifications are effective strategies for improving metabolic stability [1]
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Louandre C, Ezzoukhry Z, Godin C, Barbare J-C, Mazire J-C, Chauffert B et al (2013) Iron-dependent cell death of hepatocellular carcinoma cells exposed to sorafenib
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