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Semaglutide (4,113.6 Da) is a human GLP-1 analog, similar to liraglutide but engineered to have increased albumin affinity and resistance to dipeptidyl peptidase-4 (DPP-4) inhibitor degradation to permit once-weekly subcutaneous administration [12, 23]

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Indeed, hyperinsulinemia-mediated increases in TKT expression are directly correlated to the development of MAFLD