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doi:10.1186/s10020-022-00577-3
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Planta 157, 441445
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A peptide that survives the stomach intact still faces intestinal brush-border peptidases and first-pass hepatic metabolism before it can reach systemic circulation
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Across preclinical research and clinical studies, cagrilintide has been evaluated for effects on body weight, energy intake, and metabolic parameters, including work that explores combination approaches (such as pairing with semaglutide)
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