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Each time a cell divides, its telomeres shorten slightly, a process the National Human Genome Research Institute describes in its explanation of how telomeres protect chromosomes

N Engl J Med 332:292297 Feuerstein JD, Ho EY, Shmidt E, Singh H, Falck-Ytter Y, Sultan S, Terdiman JP, Sultan S, Cohen BL, Chachu K (2021) AGA clinical practice guidelines on the medical management of moderate to severe luminal and perianal fistulizing Crohns disease

This represents true muscle cell multiplication rather than just size increase

All of these adducts were formed via iminium ions, reactive intermediates on the piperazine ring

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