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Temporary menstrual irregularities may occur during treatment due to rapid weight loss, but these are generally reversible and do not indicate permanent reproductive damage

Although folic acid supplementation has been proven effective to control circulating homocysteine concentrations, homocysteine lowering has not affected the incidence of cardiovascular disease in supplementation trials

Patel encourages finding enjoyable movement routines tailored to individual capabilities, promoting long-term adherence

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Some patients have been hospitalized after accidental overdoses when using vials that require self-measurement