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Overarching Principle The fundamental principle of regulation of medicines is to optimise timely access to effective treatments while reducing the risk of harm from improper use

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All in vitro experiments were biologically replicated at least three times, and the specific numbers of animals used in each experiment are detailed in the corresponding figure legends

While these programs may improve access for eligible patients, many consumers still face coverage limits, eligibility requirements, and out-of-pocket costs that influence which options they consider