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Inflammatory mediators such as histamine, proteolytic enzymes, glycolytic enzymes, and heparin, as well as de novo synthesized prostaglandin D2 (PGD2), leukotriene C4 (LTC4), adenosine, and ROS are released from mast cell granules (34), and they directly induce oxidative stress ( Figure 1 )

2011 Oct;52 Suppl 8(Suppl 8):45-7

doi:10.1039/D1MD00083G

Enzymatic Cleavage Process : Once S-Acetyl L-Glutathione reaches cells, specific enzymes cleave off the protective acetyl group, releasing active glutathione directly where it's needed most for cellular health and antioxidant defense

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