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These effects have been attributed to improvements in insulin sensitivity, modulation of lipid metabolism, and activation of enteroendocrine and thermogenic gene programs

Heymsfield, MD, Professor of Medicine at the Pennington Biomedical Research Center

] Uribe PM, Kawas LH, Harding JW, Coffin AB

Guidelines for T2D Therapy When Weight is a Primary Concern The treatment guidelines for T2D from the American Diabetes Association (ADA) have undergone significant paradigm changes in recent years, and have prioritized the individualization of therapy according to patients needs and comorbidities [20]