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Impairments to the GH-IGF-I axis in hSOD1G93A mice give insight into possible mechanisms of GH dysregulation in patients with amyotrophic lateral sclerosis
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The primary endpoint was the percentage of people with at least one GI adverse event during the initiation and titration observation period, stratified by whether they were also taking metformin
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Different to baseline, at 4 months NADPH associated with several metabolite of purine metabolism, such as hypoxanthine, inosine monophosphate (IMP), cyclic adenosine monophosphate (cAMP) and allantoin (Fig
