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In breast tumours, elevated transferrin receptor (TFRC) expression and reduced ferroportin (SLC40A1) levels promote iron accumulation and correlate with poor prognosis (7173) TNBC, in particular, displays heightened iron dependency, reflecting its aggressive phenotype and metabolic plasticity (7476)
doi: 10.1542/peds.2017-1811 91 FranzCMHuchMAbriouelHHolzapfelWGlvezA
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BMJ Case Rep 2025;18(1):e263899
Clinical data sources All clinical trial data cited in this report is drawn from peer-reviewed publications in The New England Journal of Medicine and The Lancet, and investor disclosures from Novo Nordisk and Eli Lilly
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