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Patients with obesity but without major depressive disorder or suicidal ideation within the previous 2 years attained meaningful weight loss with semaglutide, regardless of antidepressant use at baseline, in a post-hoc analysis of the Semaglutide Treatment Effect in People with Obesity (STEP) program
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Hence, the effects of GLP-1 RA on the central nervous system may contribute to the induction of weight loss but not necessarily to its maintenance
Trichlormethiazide Diuril The therapeutic efficacy of Semaglutide can be decreased when used in combination with Trichlormethiazide
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