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These findings, while not directly translatable to human dosing, provide the strongest available evidence base for clinical decision-making
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Medication-related weight change can also have more than one cause
Lipoic acid might be able to increase glutathione synthesis in aged rats by up-regulating the expression of -glutamylcysteine ligase (-GCL), the rate-limiting enzyme in glutathione synthesis (31), and by increasing cellular uptake of cysteine, an amino acid required for glutathione synthesis (32)
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