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The mtDNA methylation involved may be a potential mechanism for exposure to L-carnitine, TMAO, and atherosclerotic biomarkers (40)

Metabolite-mediated PTMs of proteins undoubtedly play a vital role in tumor cells, affecting both histones and non-histone proteins, covering modifications such as lactylation, crotonylation, acetylation, palmitoylation, and succinylation

Doctors monitor patients for side effects, adjust dosages, and evaluate treatment progress