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An RCT in patients receiving cisplatin chemotherapy found that NAC (1,200 mg/day) significantly reduced nephrotoxicity and ototoxicity without reducing antitumor efficacy (Riga et al., Am J Clin Oncol, 2013) [77]
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The move, the spokesperson added, was due to a lack of compelling efficacy in the studied patient population
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Aliment.Pharmacol Ther 2011;34(9):1088-1097
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