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[10] [11] When semaglutide binds to GLP-1 receptors in the gut, it slows gastric emptying, meaning food moves more slowly from the stomach into the small intestine

In addition, the spacing between prescriptions is irregular in routine care and may partly reflect the observation process itself

A C18 fatty diacid chain attached to lysine at position 26 via a hydrophilic spacer enables reversible binding to serum albumin extending the half-life from approximately 2 minutes (native GLP-1) to approximately 7 days

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