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Who benefits most B12 shots make the biggest difference for people who are genuinely low, including vegans and vegetarians, older adults, and people with conditions like Crohn's disease that limit absorption

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In general, the controls could not heal cysteamine colitis and colon-colon anastomosis

reviewed the evidence as to whether any of the available forms of B12 are superior, and concluded that all forms can be converted to the active methyl- and adenosyl-B12 forms, and that there was not sufficient evidence to suggest that any form was superior in terms of bioavailability, biochemical effects or clinical efficacy