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The largest changes reported in studies occurred over several months while participants continued treatment and dose escalation
The landmark SELECT trial demonstrated that weekly semaglutide 2.4 mg reduces major cardiovascular events by 20% in people with obesity or overweight and established heart diseaseeven in those without diabetes.[1] This finding represents a paradigm shift in cardiovascular prevention, as it's the first time a weight-loss medication has been proven to directly reduce heart attacks, strokes, and cardiovascular deaths
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