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ber drei pharmakologische Hauptmechanismen VEGF-Aktivierung mit Angiogenese-Frderung (Neubildung von Blutgefen in geschdigtem Gewebe), Stickstoffmonoxid-Signalweg-Aktivierung fr Mikrozirkulation und anti-entzndliche Wirkung, sowie Wachstumsfaktor-Modulation (EGR-1, FAK) fr Zell-Migration und Geweberegeneration
Citation16 Many summaries of commercially available products, their formulations, and the rationale behind typical formulation components are available
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The inter-monomer hydrogen bonds were destabilized and water-mediated hydrogen bonds were more prominent in the mutated insulin dimer, which disrupted the anti-parallel -sheet formed by the C-terminus of the B-chain at the monomer-monomer interface, thereby decreasing the stability of the insulin dimer
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