l-tryptophan metabolism is the most prominent pathway that undergoes HMRD during SARS-CoV-2 infection
doi: 10.1038/sj.ijo.0801083 Summary Keywords Prader-Willi syndrome, obesity, GLP-1 receptor agonist, semaglutide, metabolic surgery Citation Koceva A, Mleku Kozamernik K, Jane A, Herman R, Ferjan S and Jensterle M (2025) Case report: Long-term efficacy and safety of semaglutide in the treatment of syndromic obesity in Prader Willi syndrome - case series and literature review
How GLP-1/GIP dual agonists work for weight loss GLP-1/GIP dual agonists (or "co-agonists") mimic the actions of two peptide hormones, GLP-1 and GIP
Summary Integrating GLP-1 RA therapy with tailored resistance exercise and caloric restriction with dietary counseling, including adequate protein intake (1.21.6 g/kg/day), may help preserve muscle mass and function in older adults
In the end, SURMOUNT-4 is a trial that studies BW preservation in participants with obesity or overweight