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Two incretin hormones GLP-1 and GIP: Comparison of their actions in insulin secretion and cell preservation

As PTDM and chronic kidney disease are prevalent comorbidities in liver transplant patients, and with the increasing trend of obesity, it is crucial to further investigate and understand the potential benefits and challenges of utilizing GLP-1 RAs and SGLT-2 inhibitors in this population

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In this regard, dexamethasone increased the expression of carnitine palmitoyltransferase I (CPT1) in human myeloid-derived suppressor cells, leading to an increase in fatty acid oxidation, mitochondrial respiration, and enhanced immunosuppressive activity (178)

Taniguchi CM, Emanuelli B, Kahn CR