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Similar findings were recently reported in primary renal proximal tubular cells from uninephrotectomized rats ( Xenopus laevis oocytes microinjected with the DIC cRNA from rat liver did not result in significant GSH transport activity (Martensson et al., 1990)

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Exploratory aims Exploratory aims are to evaluate the change from baseline that treatment with 400 mg oral SAMe for 180 days has, compared to placebo, on 1) blood total tau, amyloid-, and neurofilament light levels, and 2) cognitive status as assessed by the Standardized MiniMental State Examination, Cognitive Dementia Rating, California Verbal Learning Test 3rd Edition, Montreal Cognitive Assessment, and Digit Symbol Substitution Test

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