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[7] While kava appears safe in traditional South Pacific use, caution is advised, especially during pregnancy, for people with preexisting liver conditions, or when combined with alcohol consumption, prescription drugs or dietary supplements

such patients with regular and chronic ethanol consumption be monitored for the desired therapeutic response to vitamin B12

This ensures that the body maintains optimal levels of Methionine, Inositol, Choline, and B12, so you can maximize fat metabolism and detoxification

For instance, SGLT2 inhibitors may be added if first-line therapies such as diet and lifestyle changes plus metformin are insufficient