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Its hard to know what to believe
It consists of 15 amino acids and is stable in human gastric juice, a characteristic that distinguishes it from many other bioactive peptides in preclinical research
Different MC4R variants differently impact on receptor signaling, making it difficult to predict which patients would respond to agonist therapy
Conditional analysis did not identify independent associations within the locus for either trait (Extended Data Fig
Very few have used it that long outside of clinical trials, so rare or late risks are not fully known
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