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Montero et al., 2010

Boccal/sublingual administration provides comparable results to glutathione IV

When the body is in a state of hypoxia, infection, intense exercise, etc, and the cells demand for ATP increases, pyruvate and NADH tends to be directly catalyzed by lactate dehydrogenase (LDH) to produce lactate, rather than entering the mitochondria to participate in the tricarboxylic acid cycle (TCA)

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This form of glutathione is essential to many different enzymes in the body