Once bound to the IGF-1 receptor 3 (IGF-1R), it triggers key anabolic pathways such as Akt/mTOR , stimulating protein synthesis, cellular growth, and repair
This includes enlarged hands, feet, jaw, and internal organ enlargement (for example: heart, liver)
Meanwhile, 5-amino-1MQ provides excellent bioavailability characteristics suited for specialized chemical processes
For a 100mg vial targeting 5mg per dose at 0.25mL injection volume: 100mg 5mg = 20 doses
After PBS wash 2~3 times, cells were maintained in serum-free RPMI 1640 medium (Gibco, Thermo Fisher Scientific) for the duration of the assay