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Apoptotic changes such as pyknotic [50] and fragmented nucleus, condensed chromatin [51], fragmented cytoplasm [52], disorganization of organelles [53], shrinkage of the whole cell and breakdown into apoptotic bodies are typical for degenerated blastomers [54]
coli After having selected the enzymes for the L-carnitine biosynthetic pathway, expression of the four genes was optimized by combining the individual genes in a single plasmid as a synthetic operon
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