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This complexation is what makes the molecule biologically active and effective
Yuan, H., Li, X., Zhang, X., Kang, R
Additionally, it was reported that trimetazidine (TMZ), a piperazine derivative, mediated activation of the GSH system and had antioxidant and cytoprotective effects in several myocardial injury models [210,211,212,213]
Especially due to hypoxia, the heart is one of the most metabolically active organs in the body, and myocardial metabolism is highly sensitive to ischemia and hypoxia
Many individuals cycle through active treatment and maintenance phases over extended periods
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