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Despite the fact that it has been known for over 40 years that there is a requirement for Methylation in the production of melatonin via the enzyme HIOMT (Pevet etal, 1980), treatment for poor sleep in ASD by correction of functional B12 deficiency is generally not attempted (Souders etal, 2017
The most common adverse reactions reported in clinical trials were injection site reactions (erythema, pruritus, pain) occurring in approximately 8-13% of patients
Unlike our previous study 12 , we used a broader dissection strategy encompassing the entire DVC
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