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Pharmaceutical GLP-1 analogs work by mimicking and extending the activity of this natural hormone - producing the appetite-suppressing and metabolic effects at sustained concentrations that the natural hormone, which is rapidly degraded by the enzyme DPP-4, can't maintain on its own

This distinction is especially important because the FDA has warned that many weight loss products marketed as supplements may contain hidden drug ingredients, may be falsely advertised as natural products, and can pose serious health risks

Trial populations and endpoints differ, and outcomes vary from person to person

The cost savings could make these drugs accessible to patients who simply couldnt afford them before

Some studies have shown that results can be achieved on microdoses, but they havent been validated in evidence-based guidelines, says DeGore