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In line with this observation, our comprehensive transcriptome analysis of paired tumor specimens obtained before (PreNAC) and after (PostNAC) CF-based NAC revealed that 14 GSH metabolismrelated genes were highly expressed in recurrent tumors at the PreNAC stage, the PostNAC stage, or both, supporting the notion that resistance-associated molecular programs are often established prior to chemotherapy rather than being broadly acquired during NAC
References Abd El-Ghafar OAM, Hassanein EHM, Ali FEM, Omar ZMM, Rashwan EK, Mohammedsaleh ZM, Sayed AM (2022) Hepatoprotective effect of acetovanillone against methotrexate hepatotoxicity: role of Keap-1/Nrf2/ARE, IL6/STAT-3, and NF-B/AP-1 signaling pathways
Medicare Supplement insurance is available to those age 65 and older enrolled in Medicare Parts A and B and, in some states, to those under age 65 eligible for Medicare due to disability or End-Stage Renal disease
