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this is trigger linked to metabolism of sugars and lipids

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Anastomoses between two defects in the corresponding tissues (i.e., in esophagus and skin (Skorjanec et al., 2009), duodenum and skin (Skorjanec et al., 2015), colon and skin (Klicek et al., 2008), colon and bladder (Grgic et al., 2016), and rectum and vagina (Sikiric et al., 2020a)

3b), which correlates with the milder lifespan increase in the fem-3(-) compared to the glp-1(-) mutant

Up to 30% of mCRPC tumors harbor DNA damage repair gene aberrations, 24 which can be therapeutically used with PARP inhibitors to induce synthetic lethality