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715,716 In this section, we have summarized the findings of in vivo studies investigating the applications of probiotics (Table 1) and prebiotics (Table 2) in neurodegenerative disease models, with a specific focus on their effects on the intestinal barrier, BBB, and glial cells

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Efficacy was assessed by the TRE (all randomized participants, regardless of whether they adhered to treatment) and the efficacy estimand (randomized participants who completed the planned treatment course)

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