tirzepatide and running Semaglutide & Naples Does tirzepatide make you tired?

Can tirzepatide (dual GIP/GLP1 receptor agonist) be used offlabel to treat an overweight/obese woman with polycystic ovary syndrome and insulin resistance who has not responded to diet, exercise, and metformin, and what dosing and safety monitoring are recommended?

These include pancreatitis, vision problems like NAION or worsening diabetic retinopathy, low blood sugar when taken with insulin or sulfonylureas, acute kidney injury, severe digestive issues such as gastroparesis or ileus, allergic reactions, gallbladder disease and a higher risk of aspiration during surgery because Ozempic slows digestion

Asian Australas J Anim Sci (2018) 31(4):55663

Ward A, Crean S, Mercaldi CJ, Collins JM, Boyd D, Cook MN, et al

Month 1: 0.5 mg, once daily Month 2: 1 mg, once daily Month 3: 1.5 mg, once daily Month 4: 2 mg, once daily Month 5 and beyond (maintenance): 2.5 mg, once daily Medication is prescribed only after consultation with a licensed provider to determine appropriateness