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This intelligent modulation suits chronic conditions where the goal is restoration of normal function rather than complete suppression
Aminoglycosides, tetracyclines, and certain other antibiotics may alter gut microbiota composition, potentially affecting the small amount of vitamin B12 that is produced by colonic bacteria, though this is generally not clinically significant for patients receiving injectable B12 supplementation
For patients who have not previously been diagnosed with vitamin B12 deficiency or prescribed a vitamin B12 injection, the medicine can be offered if vitamin B12 deficiency is suspected based on signs, symptoms and/or risk factors, though confirmation of vitamin B12 deficiency by a reliable test kit should also be considered
This flood of NAD+ in the fat cells forces them to continuously burn energy rather than store it, leading to rapid reductions in fat mass without the need for dietary changes in animal models
Beyond just energy, B12 can also support a more stable mood and may even help with symptoms of depression
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