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TLK-286: a novel glutathione S -transferase-activated prodrug
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Glutathione sits at the center of the bodys antioxidant defense system
First week felt like nothing changed
Redox potential assessed by cyclic voltammetry ROS production involves cycling between Cu(I) and Cu(II) states, so we reasoned that the difference in ROS production between the different Cu:peptide complexes might be related to the energetics of this transition
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