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Avoiding caffeine and alcohol, which can worsen diarrhea and dehydration, is advisable during symptomatic periods
First, it has been observed to prevent mast cell activation more effectively than antihistamines
Naunyn-Schmiedeberg's Arch Pharmacol 399 , 25772591 (2026)
The logic is identical: a sub-therapeutic priming dose lets the gut and central receptors acclimatise before the standard ladder begins
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