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However, most carnitines, being quaternary ammonium cation complexes, exist in ionized states under RP-LC conditions, leading to weak chromatographic retention

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The mechanism of action overlaps substantially with the physiological changes produced by bariatric surgery itself, particularly Roux-en-Y gastric bypass and sleeve gastrectomy, which both increase endogenous GLP-1 secretion

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L-Propionylcarnitine (chloride) stimulates energy production in ischemic muscles by increasing citric acid cycle flux and by stimulating pyruvate dehydrogenase activity