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In the PIONEER PLUS trial, for individuals with type 2 diabetes, a daily dose of 50 mg oral semaglutide achieved a weight loss of 9.8% over a continuous 68-week study period compared to 5.4% weight loss with a daily dose of 14 mg semaglutide

Overall, adults experienced approximately 11% weight loss at the highest dose studied

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Improvements in metabolic and inflammatory markers Beyond weight loss and body composition, the study also identified several favourable metabolic changes

Freezing unreconstituted peptides is generally acceptable but unnecessary if you plan to use them within their stated shelf life