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The 48-68 hour steady-state half-life comfortably supports once-daily dosing with relatively stable plasma concentrations throughout the dosing interval

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Next-generation oral candidates like orforglipron promise improved bioavailability and dosing flexibility without requiring special storage conditions or meal timing [2]

Finally, fructo-oligosaccharides (FOS) , soluble dietary fibres found in certain plants such as garlic, onions and bananas, are being studied for their potential ability to modulate the intestinal microbiota and thus encourage the production of GLP-1