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In cancer and other diseases, metabolic changes can lead to epigenetic modifications, such as those caused by oncometabolites that disrupt DNA methylation and histone demethylation, contributing to tumorigenesis

Alopecia areata (AA) is an autoimmune dermatologic disease characterized by partial or complete hair loss of the scalp (alopecia totalis) or the entire body (alopecia universalis), with a variable and unpredictable course

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Supporting Study: Wessells, H., et al

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