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Although FOXO4s specific effects on mitochondria are as direct as the other peptides above, it is known to regulate the expression of genes involved in oxidative stress response and energy metabolism, which can impact mitochondrial function indirectly (Liu, 2019)

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In addition, ferroptosis is hypothesized to depend on intracellular iron concentration (8)

We also analysed whether persistent GLP-1RA users experienced fewer cardiovascular outcomes and lower all-cause mortality than non-persistent patients