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Although it displays a very similar pharmacological profile to that of exenatide, lixisenatide is given once-daily with a dose of 10 or 20 g
Reconstitution math (3.0 mL BAC water, 3 mL vial) Vial 10/3 Total mg 13 mg Concentration 4.33 mg/mL total 10 units (0.10 mL) delivers 0.33 mg tes + 0.10 mg ipa Vial 5/5 Total mg 10 mg Concentration 3.33 mg/mL total 10 units (0.10 mL) delivers 0.167 mg tes + 0.167 mg ipa 3.0 mL is the practical maximum for this 3 mL vial
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The equilibrium between bone production and resorption is therefore preserved by VDR activation
Pharm Res 32:121 Catrina S-B, et al (2024) PIONEER REAL Sweden: a multicentre, prospective, real-world observational study of oral semaglutide use in adults with type 2 diabetes in Swedish clinical practice
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