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Taken together, the translational potential for clinical applications for NTFs remains exciting, however, while strategies how to pass the BBB are on the horizon, little is known about potential deleterious consequences of NTFs in the complex neuroimmune crosstalk in MS for an early use in clinical studies

Several states (e.g., North Carolina, California, Connecticut, Rhode Island, Michigan) have paused or proposed ending Medicaid coverage for GLP1 drugs for weight loss due to escalating costs, while continuing coverage for diabetes or cardiovascular risk indications

1a) [25, 26]

Newer oral GLP-1 options like the Wegovy pill are more affordable currently around $149 per month but clinical trials show they deliver somewhat less weight loss than injectables, averaging around 1516% compared to 20% or more with injections. For patients who need significant weight loss to resolve health conditions, a lower-cost medication that produces fewer results may not be enough