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Vitamin C is a powerful anti-oxidant and is utilized by phase 1 liver detoxification pathways
Of the total adverse events reported, 37% were gastrointestinal in nature [207 events in 73 (77%) of 95 participants], most frequently nausea [67 events in 53 (56%) participants], vomiting [43 events in 23 (24%) participants], and dyspepsia [32 events in 27 (28%) participants]
That can increase the risk of cardiovascular disease
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Kawas LH, McCoy AT, Yamamoto BJ, Wright JW, Harding JW
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