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Due to the lack of a domain directly binding to membrane phospholipids, the localization and activation of DRP1 in mitochondria rely on receptor proteins and recruitment factors on the mitochondrial surface [88]
In this way, our study extends previous descriptive observations of biodegradable MP neurotoxicity to a mechanistic level [35], identifying microglial lipotoxicity as a previously unrecognized link between intestinal PBAT-MPs exposure and neuronal dysfunction
The hydrochloride salt (CHClNO) is the most common commercial form, appearing as a white to off-white crystalline powder with a melting point of approximately 194C
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